Core
Technology.
01
Supercritical fluid-based ECM molecular size reduction
13,520 Da
3,089 Da
Hydrolyzed dECM showed a reduction in molecular weight from 13,520 Da to 3,089 Da while preserving key ECM components, and fluorescence analysis confirmed its delivery into the dermal layer.
02
Fibroblast activation and ECM remodeling induced by hydrolyzed dECM
Hydrolyzed dECM activated fibroblasts and increased CTGF expression by approximately 2.8-fold, demonstrating a biological response associated with ECM remodeling.
03
VEGF Upregulation observed with hydrolyzed dECM
Increased VEGF expression indicates a biological response associated with angiogenesis and the regenerative microenvironment.